|
In Vivo, Hypothalamic Deep Brain Stimulation (DBS)
for Weight Loss in Rat Obesity Model.
Evaluating the feasibility and effectiveness of chronic
deep brain stimulation of the feeding center, ventromedial
hypothalamus (VHM) of obese rats to effect weight loss. 2003
NeuroGrant Recipient
Deep Brain Stimulation for Treatment of Obesity: Chronic
Stimulatory Inhibition of the Lateral Hypothalamic Area and
Effects on Food Intake and Weight in the Rat
Evaluating the feasibility and effectiveness of chronic
deep brain stimulation to the lateral hypothalamus of obese
rats to effect weight loss.
A Direct Brain-to-Speech Generator for Use in Humans
Investigating the possibility of direct brain-to-speech
activity in locked-in patients. 2004 NeuroGrant Recipient
Chronic Bilateral Deep Brain Stimulatory Inhibition
of the Lateral Hypothalamus for Treatment of Obesity in the
Primate
To determine if bilateral deep brain stimulation of
the Lateral Hypothalamus will lead to significant and sustained
weight loss in primates. 2004 NeuroGrant Recipient
Trigeminal Neuralgia
Patient and Provider Education Program
Training program for providers and the community to
increase awareness and improve treatment for patients suffering
from trigeminal neuralgia. 2005 NeuroGrant Recipient
Impact of Deep Brain Stimulation in the Sub-Thalamic
Nucleus of Patients with Parkinson’s Disease on Behavior
and Mood
Prospective longitudinal study to assess the impact
of deep brain stimulation on behavior and mood in patients
with idiopathic Parkinson’s Disease. 2005 NeuroGrant
Recipient
Safety and Efficacy of Deep Brain Stimulation (DBS)
of the Globus Pallidus Internus (Gpi) in Dystonia
Assessing the safety and efficacy of bilateral deep
brain stimulation of the Globus Pallidus Internus in medically
refractory dystonia. 2003 NeuroGrant Recipient
Quality of Life Outcomes and Caregiver Burden in Patients
with Advanced Parkinson’s Disease Treated with Unilateral
Deep Brain Stimulation of the Sub-Thalamic Nucleus
To determine the impact of unilateral deep brain stimulation
of the Sub-Thalamic Nucleus (STN) on self reported quality
of life measures and perceived caregiver burden in patients
with advanced Parkinson’s disease and their families.
2004 NeuroGrant Recipient
Host Immunological Response to Transplantation
of Stem Cells
Evaluating the immunological potential for the rejection
of stem cell grafts in the treatment of MPTP-induced Parkinson-like
symptoms. 2005 NeuroGrant Recipient
Microelectrode Signal Analysis
Elucidating the pathophysiology of patients with unusual
diseases undergoing deep brain stimulation through the analysis
of firing patterns. 2005 NeuroGrant Recipient
Transplantation of Human Stem Cells of Hematopoietic Origin into a 6-Hydroxydopamine Rodent Model of Parkinson's Disease: To Repair, Replace, or Regenerate Dopaminergic Tissue in the Nigral-Striatal Pathway.
To determine the viability and potential for human hematopoietic stem cells either in their heterogeneous form or directed toward a DA phenotype, to repair, replace, or regenerate the loss of DA in the striatum in rats pre-treated with a DA neurotoxin. 2007 NeuroGrant Recipient
Adult Hippocampal Neurogenesis in Mouse Models of Familial Alzheimer's Disease
To elucidate the molecular mechanisms underlying the effect at early onset Familial Alzheimer's Disease (FAD)-linked Presenilin 1 on adult neurogenesis. 2008 NeuroGrant Recipient
|
